Ancestral Reconstruction & Selection Analysis

Comparing HyPhy MEME selection mapping between Legacy (43 species) and Full TOGA (581 species) alignments for the AOX1 gene.

Select Site:
Comparative Selection Metrics
Metric Legacy Tree TOGA Tree
Sequences 43 581
Codon Position Site 697 Site 744
MEME p-value 0.0002 0.6667
LRT Statistic 15.13 0.00
Inferred Selection Rate (β+) 117.8 0.0
Reconstructed Mutations 2 Non-syn 10 Non-syn, 5 Syn
Branch mutation HETGLA Non-synonymous Synonymous
Non-synonymous mutation
Synonymous mutation
No change (neutral)
Biological Explanation & Analysis
Legacy Tree (43 species) Subsampled
TOGA Tree (581 species) Full Dataset