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[0, 0, 1, 0, 0, 0, 1, 0, 0, 0, 0],
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]
},
"headers": [
["alpha;", "Synonymous substitution rate at a site"],
["β-", "Non-synonymous substitution rate at a site for the negative/neutral evolution component"],
["p-", "Mixture distribution weight allocated to β-; loosely -- the proportion of the tree evolving neutrally or under negative selection"],
["β+", "Non-synonymous substitution rate at a site for the positive/neutral evolution component"],
["p+", "Mixture distribution weight allocated to β+; loosely -- the proportion of the tree evolving neutrally or under positive selection"],
["LRT", "Likelihood ratio test statistic for episodic diversification, i.e., p+ > 0 and β+ > α"],
["p-value", "Asymptotic p-value for episodic diversification, i.e., p+ > 0 and β+ > α"],
["# branches under selection", "The (very approximate and rough) estimate of how many branches may have been under selection at this site, i.e., had an empirical Bayes factor of 100 or more for the β+ rate"],
["Total branch length", "The total length of branches contributing to inference at this site, and used to scale dN-dS"],
["MEME LogL", "Site Log-likelihood under the MEME model"],
["FEL LogL", "Site Log-likelihood under the FEL model"]
]
},
"analysis":{
"authors":"Sergei L. Kosakovsky Pond, Steven Weaver",
"citation":"Detecting Individual Sites Subject to Episodic Diversifying Selection. _PLoS Genet_ 8(7): e1002764.",
"contact":"spond@temple.edu",
"info":"MEME (Mixed Effects Model of Evolution)\n estimates a site-wise synonymous (α) and a two-category mixture of non-synonymous\n (β-, with proportion p-, and β+ with proportion [1-p-]) rates, and\n uses a likelihood ratio test to determine if β+ > α at a site.\n The estimates aggregate information over a proportion of branches at a site,\n so the signal is derived from\n episodic diversification, which is a combination of strength of selection [effect size] and\n the proportion of the tree affected. A subset of branches can be selected\n for testing as well, in which case an additional (nuisance) parameter will be\n inferred -- the non-synonymous rate on branches NOT selected for testing. Multiple partitions within a NEXUS file are also supported\n for recombination - aware analysis.\n ",
"requirements":"in-frame codon alignment and a phylogenetic tree",
"version":"2.1.2"
},
"branch attributes":{
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"original name":"epi_isl_412980_Hubei_20200118_Nextseq550_117"
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"original name":"epi_isl_413023_Zurich_20200229_Illumina_1"
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"original name":"epi_isl_413221_Scotland_20200302_Nanopore_15"
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"original name":"epi_isl_413485_Anhui_20200124_null_1"
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"epi_isl_413550_Lagos_20200227_Illumina_1":{
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"original name":"epi_isl_413550_Lagos_20200227_Illumina_1"
},
"epi_isl_413557_California_2020_Illumina_1":{
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"original name":"epi_isl_413557_California_2020_Illumina_1"
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"original name":"epi_isl_413564_Andel_20200301_Nanopore_5"
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"epi_isl_413566_Blaricum_20200302_Nanopore_49":{
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"Nucleotide GTR":0.0001321687545254189,
"original name":"epi_isl_413566_Blaricum_20200302_Nanopore_49"
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"epi_isl_413586_Tilburg_20200227_Nanopore_1":{
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"original name":"epi_isl_413586_Tilburg_20200227_Nanopore_1"
},
"epi_isl_413593_Luxembourg_20200229_Nanopore_3":{
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"original name":"epi_isl_413593_Luxembourg_20200229_Nanopore_3"
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"epi_isl_413601_Washington_20200302_Illumina_1":{
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"original name":"epi_isl_413601_Washington_20200302_Illumina_1"
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"original name":"epi_isl_413605_Helsinki_20200301_Illumina_1"
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"epi_isl_413753_China_2020_02_MGI_1":{
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"Nucleotide GTR":0.0002797065484835541,
"original name":"epi_isl_413753_China_2020_02_MGI_1"
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"original name":"epi_isl_413791_China_2020_02_MGI_2"
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"epi_isl_413809_China_2020_02_MGI_1":{
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"original name":"epi_isl_413809_China_2020_02_MGI_1"
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"epi_isl_413850_Guangdong_20200210_metagenomics_BGI_1":{
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"original name":"epi_isl_413850_Guangdong_20200210_metagenomics_BGI_1"
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"original name":"epi_isl_413851_Guangdong_20200130_metagenomics_BGI_1"
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"original name":"epi_isl_413855_Guangdong_20200207_metagenomics_BGI_2"
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"original name":"epi_isl_413856_Guangdong_20200207_metagenomics_BGI_1"
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"epi_isl_413863_Guangdong_20200201_metagenomics_BGI_1":{
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"original name":"epi_isl_413863_Guangdong_20200201_metagenomics_BGI_1"
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"original name":"epi_isl_413864_Guangdong_20200209_metagenomics_BGI_2"
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"epi_isl_413871_Guangdong_20200228_multiplex_pcr_nanopore_1":{
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"original name":"epi_isl_413871_Guangdong_20200228_multiplex_pcr_nanopore_1"
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"original name":"epi_isl_413874_Guangdong_20200212_multiplex_pcr_nanopore_1"
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"original name":"epi_isl_413887_Guangdong_20200201_multiplex_pcr_nanopore_1"
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"epi_isl_413996_Tessin_20200224_Illumina_4":{
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"original name":"epi_isl_413996_Tessin_20200224_Illumina_4"
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"epi_isl_413997_Geneva_20200226_null_1":{
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"original name":"epi_isl_413997_Geneva_20200226_null_1"
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"epi_isl_413999_Argovie_20200227_null_1":{
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"epi_isl_414005_England_20200225_Illumina_3":{
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"epi_isl_414008_England_20200227_Illumina_1":{
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"original name":"epi_isl_414008_England_20200227_Illumina_1"
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"epi_isl_414013_England_20200301_Illumina_9":{
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"original name":"epi_isl_414013_England_20200301_Illumina_9"
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"epi_isl_414014_Sao_Paulo_20200302_Ion_2":{
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"original name":"epi_isl_414014_Sao_Paulo_20200302_Ion_2"
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"epi_isl_414025_Scotland_20200301_Nanopore_10":{
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"original name":"epi_isl_414025_Scotland_20200301_Nanopore_10"
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"epi_isl_414363_Washington_20200304_Illumina_1":{
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"original name":"epi_isl_414431_Noord_Brabant_20200302_Nanopore_1"
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"original name":"epi_isl_414459_Noord_Brabant_20200306_Nanopore_1"
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"original name":"epi_isl_414499_North_Rhine_Westphalia_20200226_Nanopore_1"
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"epi_isl_414521_Munich_20200302_Illumina_1":{
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"original name":"epi_isl_414521_Munich_20200302_Illumina_1"
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"epi_isl_414524_England_20200301_Illumina_1":{
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"epi_isl_414528_Hong_Kong_20200210_Illumina_2":{
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"original name":"epi_isl_414528_Hong_Kong_20200210_Illumina_2"
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"epi_isl_414542_Noord_Brabant_2020_03_Nanopore_8":{
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"original name":"epi_isl_414542_Noord_Brabant_2020_03_Nanopore_8"
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"Nucleotide GTR":0.0002643798382774121,
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"original name":"epi_isl_414590_Minnesota_20200309_Nanopore_1"
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"epi_isl_414594_Washington_20200305_Illumina_1":{
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"epi_isl_414617_USA_20200308_Illumina_1":{
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"original name":"epi_isl_414640_Finland_20200301_Illumina_1"
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"epi_isl_414935_Shandong_20200121_null_1":{
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"Nucleotide GTR":0.0001321731801308698,
"original name":"epi_isl_414935_Shandong_20200121_null_1"
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"original name":"epi_isl_414938_Shandong_20200124_null_2"
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"epi_isl_415041_Wales_20200307_Nanopore_1":{
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"Nucleotide GTR":0.0002705292972350702,
"original name":"epi_isl_415041_Wales_20200307_Nanopore_1"
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"epi_isl_415105_Bahia_20200304_Nanopore_1":{
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"original name":"epi_isl_415105_Bahia_20200304_Nanopore_1"
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"epi_isl_415130_England_20200301_Illumina_1":{
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"original name":"epi_isl_415130_England_20200301_Illumina_1"
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"epi_isl_415131_England_20200229_Illumina_1":{
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"Nucleotide GTR":0.0002788802242206516,
"original name":"epi_isl_415131_England_20200229_Illumina_1"
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"epi_isl_415136_England_20200229_Illumina_1":{
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"Nucleotide GTR":0.0001365703239717941,
"original name":"epi_isl_415136_England_20200229_Illumina_1"
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"epi_isl_415138_England_20200302_Illumina_1":{
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"original name":"epi_isl_415138_England_20200302_Illumina_1"
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"epi_isl_415139_England_20200301_Illumina_1":{
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"original name":"epi_isl_415139_England_20200301_Illumina_1"
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"epi_isl_415142_England_20200302_Illumina_1":{
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"Nucleotide GTR":0.0001381168956861389,
"original name":"epi_isl_415142_England_20200302_Illumina_1"
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"epi_isl_415143_England_20200302_Illumina_1":{
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"original name":"epi_isl_415143_England_20200302_Illumina_1"
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"epi_isl_415144_England_20200227_Illumina_1":{
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"original name":"epi_isl_415144_England_20200227_Illumina_1"
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"epi_isl_415145_England_20200301_Illumina_1":{
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"Nucleotide GTR":0.0001367039870922652,
"original name":"epi_isl_415145_England_20200301_Illumina_1"
},
"epi_isl_415146_England_20200301_Illumina_1":{
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"Nucleotide GTR":0.0001333929548558132,
"original name":"epi_isl_415146_England_20200301_Illumina_1"
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"epi_isl_415147_England_20200301_Illumina_1":{
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"Nucleotide GTR":0.00039141800585019,
"original name":"epi_isl_415147_England_20200301_Illumina_1"
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"epi_isl_415148_England_20200303_Illumina_1":{
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"original name":"epi_isl_415148_England_20200303_Illumina_1"
},
"epi_isl_415149_England_20200301_Illumina_1":{
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"Nucleotide GTR":0.0004076870472151372,
"original name":"epi_isl_415149_England_20200301_Illumina_1"
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"epi_isl_415152_Panama_City_20200306_Illumina_1":{
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"Nucleotide GTR":0.001454413757829559,
"original name":"epi_isl_415152_Panama_City_20200306_Illumina_1"
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"epi_isl_415153_Huldenberg_20200303_Nanopore_1":{
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"Nucleotide GTR":0.0006850766132234935,
"original name":"epi_isl_415153_Huldenberg_20200303_Nanopore_1"
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"epi_isl_415154_Kraainem_20200301_Nanopore_1":{
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"Nucleotide GTR":0.0005330815170946307,
"original name":"epi_isl_415154_Kraainem_20200301_Nanopore_1"
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"Nucleotide GTR":0.001595031614500766,
"original name":"epi_isl_415156_Huldenberg_20200301_Nanopore_2"
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"epi_isl_415159_Leuven_20200229_Nanopore_2":{
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"Nucleotide GTR":0.0001321730811570147,
"original name":"epi_isl_415159_Leuven_20200229_Nanopore_2"
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"epi_isl_415456_Switzerland_20200229_null_2":{
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"Nucleotide GTR":0,
"original name":"epi_isl_415456_Switzerland_20200229_null_2"
},
"epi_isl_415468_Netherlands_20200310_Nanopore_4":{
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"Nucleotide GTR":0.0001321644922807955,
"original name":"epi_isl_415468_Netherlands_20200310_Nanopore_4"
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"epi_isl_415500_Noord_Brabant_20200310_Nanopore_5":{
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"Nucleotide GTR":0.0001321702432734723,
"original name":"epi_isl_415500_Noord_Brabant_20200310_Nanopore_5"
},
"epi_isl_415504_Noord_Brabant_20200309_Nanopore_1":{
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"Nucleotide GTR":0.0001321558218000948,
"original name":"epi_isl_415504_Noord_Brabant_20200309_Nanopore_1"
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"epi_isl_415510_Noord_Brabant_20200309_Nanopore_1":{
"Global MG94xREV":0.0001316605568391105,
"Nucleotide GTR":0.000132170338823722,
"original name":"epi_isl_415510_Noord_Brabant_20200309_Nanopore_1"
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"epi_isl_415513_Noord_Brabant_20200311_Nanopore_1":{
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"Nucleotide GTR":0.0001321789452521543,
"original name":"epi_isl_415513_Noord_Brabant_20200311_Nanopore_1"
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"epi_isl_415516_Noord_Brabant_20200311_Nanopore_1":{
"Global MG94xREV":0.0001316453146827881,
"Nucleotide GTR":0.0001321790504041307,
"original name":"epi_isl_415516_Noord_Brabant_20200311_Nanopore_1"
},
"epi_isl_415525_Noord_Holland_20200312_Nanopore_1":{
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"Nucleotide GTR":0,
"original name":"epi_isl_415525_Noord_Holland_20200312_Nanopore_1"
},
"epi_isl_415528_Utrecht_20200312_Nanopore_1":{
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"Nucleotide GTR":1.793257633456576e-05,
"original name":"epi_isl_415528_Utrecht_20200312_Nanopore_1"
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"epi_isl_415531_Zuid_Holland_20200309_Nanopore_1":{
"Global MG94xREV":0.0001316590465351264,
"Nucleotide GTR":0.0001321731537066442,
"original name":"epi_isl_415531_Zuid_Holland_20200309_Nanopore_1"
},
"epi_isl_415534_Zuid_Holland_20200311_Nanopore_1":{
"Global MG94xREV":0.0001345115237089068,
"Nucleotide GTR":0.0001350542091969456,
"original name":"epi_isl_415534_Zuid_Holland_20200311_Nanopore_1"
},
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"original name":"epi_isl_415538_Wales_20200312_Nanopore_1"
},
"epi_isl_415582_British_Columbia_20200304_Nanopore_1":{
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"original name":"epi_isl_415582_British_Columbia_20200304_Nanopore_1"
},
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"original name":"epi_isl_415584_British_Columbia_20200302_Nanopore_1"
},
"epi_isl_415585_British_Columbia_20200304_Nanopore_1":{
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"original name":"epi_isl_415585_British_Columbia_20200304_Nanopore_1"
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"epi_isl_415586_British_Columbia_20200305_Nanopore_1":{
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"original name":"epi_isl_415586_British_Columbia_20200305_Nanopore_1"
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"epi_isl_415587_British_Columbia_20200304_Nanopore_1":{
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"original name":"epi_isl_415587_British_Columbia_20200304_Nanopore_1"
},
"epi_isl_415588_British_Columbia_20200305_Nanopore_1":{
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"original name":"epi_isl_415588_British_Columbia_20200305_Nanopore_1"
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"epi_isl_415589_British_Columbia_20200305_Nanopore_1":{
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"original name":"epi_isl_415589_British_Columbia_20200305_Nanopore_1"
},
"epi_isl_415592_Washington_20200309_Illumina_1":{
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"original name":"epi_isl_415592_Washington_20200309_Illumina_1"
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"epi_isl_415594_Washington_20200310_Illumina_1":{
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"original name":"epi_isl_415594_Washington_20200310_Illumina_1"
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"epi_isl_415599_Washington_20200309_Illumina_1":{
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"original name":"epi_isl_415599_Washington_20200309_Illumina_1"
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"epi_isl_415600_USA_20200309_Illumina_4":{
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"original name":"epi_isl_415600_USA_20200309_Illumina_4"
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"original name":"epi_isl_415601_Washington_20200310_Illumina_1"
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"original name":"epi_isl_415615_Washington_20200308_Illumina_1"
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"epi_isl_415617_Washington_20200309_Illumina_11":{
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"original name":"epi_isl_415617_Washington_20200309_Illumina_11"
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"original name":"epi_isl_415618_Washington_20200309_Illumina_2"
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"original name":"epi_isl_415635_Scotland_20200309_Nanopore_1"
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"Nucleotide GTR":1.825022609761158e-05,
"original name":"epi_isl_415639_Scotland_20200310_Nanopore_2"
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"epi_isl_415651_Bourgogne_France_Comt_20200305_Illumina_3":{
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"original name":"epi_isl_415651_Bourgogne_France_Comt_20200305_Illumina_3"
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"epi_isl_415656_Wales_20200312_null_10":{
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"original name":"epi_isl_415656_Wales_20200312_null_10"
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"epi_isl_415658_Santiago_20200306_Illumina_2":{
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"Nucleotide GTR":0.000548600684141368,
"original name":"epi_isl_415658_Santiago_20200306_Illumina_2"
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"original name":"epi_isl_415659_Wales_20200312_null_1"
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"Nucleotide GTR":0.0001370732596236629,
"original name":"epi_isl_415702_Switzerland_20200302_null_3"
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"Nucleotide GTR":0.002517059882647999,
"original name":"epi_isl_415916_Wales_20200311_null_2"
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"epi_isl_415919_Wales_20200311_null_1":{
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"original name":"epi_isl_415919_Wales_20200311_null_1"
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"epi_isl_416044_Hangzhou_20200125_Novaseq_1":{
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"epi_isl_416140_Copenhagen_20200302_Illumina_5":{
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"original name":"epi_isl_416140_Copenhagen_20200302_Illumina_5"
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"original name":"epi_isl_416314_Hong_Kong_20200207_Illumina_1"
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"original name":"epi_isl_416328_Shanghai_20200201_Illumina_1"
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"original name":"epi_isl_416339_Shanghai_20200203_Illumina_1"
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"original name":"epi_isl_416345_Shanghai_20200204_Illumina_1"
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"original name":"epi_isl_416347_Shanghai_20200206_Illumina_1"
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"epi_isl_416351_Shanghai_20200206_Illumina_1":{
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"original name":"epi_isl_416351_Shanghai_20200206_Illumina_1"
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"original name":"epi_isl_416354_Shanghai_20200204_Illumina_1"
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"epi_isl_416368_Shanghai_20200205_Illumina_1":{
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"original name":"epi_isl_416368_Shanghai_20200205_Illumina_1"
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"original name":"epi_isl_416386_Shanghai_20200131_Illumina_1"
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"epi_isl_416389_Shanghai_20200121_Illumina_1":{
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"original name":"epi_isl_416389_Shanghai_20200121_Illumina_1"
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"epi_isl_416390_Shanghai_20200131_Illumina_1":{
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"original name":"epi_isl_416390_Shanghai_20200131_Illumina_1"
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"original name":"epi_isl_416391_Shanghai_20200202_Illumina_1"
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"epi_isl_416392_Shanghai_20200202_Illumina_1":{
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"original name":"epi_isl_416397_Shanghai_20200202_Illumina_1"
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"epi_isl_416417_Connecticut_20200310_Oxford_1":{
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"Nucleotide GTR":0,
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},
"epi_isl_416419_Connecticut_20200309_Oxford_1":{
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"Nucleotide GTR":0.0001322804327634988,
"original name":"epi_isl_416419_Connecticut_20200309_Oxford_1"
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"epi_isl_416426_Budapest_20200317_Nanopore_1":{
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"Nucleotide GTR":0.003232417185284237,
"original name":"epi_isl_416426_Budapest_20200317_Nanopore_1"
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"original name":"epi_isl_416439_Washington_20200310_Illumina_1"
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"original name":"epi_isl_416441_Washington_20200310_Illumina_4"
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"original name":"epi_isl_416442_Washington_20200310_Illumina_2"
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"original name":"epi_isl_416444_Washington_20200310_Illumina_2"
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"original name":"epi_isl_416447_Washington_20200310_Illumina_1"
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"Nucleotide GTR":0.00153451453110454,
"original name":"epi_isl_416521_Saudi_Arabia_20200310_Illumina_2"
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"epi_isl_416524_Saitama_20200311_null_3":{
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"Nucleotide GTR":0,
"original name":"epi_isl_416524_Saitama_20200311_null_3"
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"epi_isl_416538_Wellington_20200315_Nanopore_2":{
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"Nucleotide GTR":0.0001321758012012699,
"original name":"epi_isl_416538_Wellington_20200315_Nanopore_2"
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"Nucleotide GTR":0,
"original name":"epi_isl_416539_Wellington_20200315_Nanopore_3"
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"epi_isl_416543_Dasman_20200302_Illumina_1":{
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"Nucleotide GTR":0.0001321764953603996,
"original name":"epi_isl_416543_Dasman_20200302_Illumina_1"
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"Nucleotide GTR":0.0001321617121550664,
"original name":"epi_isl_416565_unknown_20200215_Illumina_1"
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"epi_isl_416566_unknown_20200215_Illumina_1":{
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"original name":"epi_isl_416566_unknown_20200215_Illumina_1"
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"epi_isl_416567_unknown_20200215_Illumina_1":{
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"Nucleotide GTR":0.0001321731772704212,
"original name":"epi_isl_416567_unknown_20200215_Illumina_1"
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"epi_isl_416568_unknown_20200215_Illumina_1":{
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"Nucleotide GTR":0,
"original name":"epi_isl_416568_unknown_20200215_Illumina_1"
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"epi_isl_416570_unknown_20200215_Illumina_1":{
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"Nucleotide GTR":0.0001321645074655358,
"original name":"epi_isl_416570_unknown_20200215_Illumina_1"
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"epi_isl_416608_unknown_20200217_Illumina_8":{
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"Nucleotide GTR":0,
"original name":"epi_isl_416608_unknown_20200217_Illumina_8"
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"epi_isl_416614_unknown_20200217_Illumina_1":{
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"Nucleotide GTR":0.0001321671216265526,
"original name":"epi_isl_416614_unknown_20200217_Illumina_1"
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"epi_isl_416619_unknown_20200217_Illumina_1":{
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"Nucleotide GTR":0.0001321731991264432,
"original name":"epi_isl_416619_unknown_20200217_Illumina_1"
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"epi_isl_416623_unknown_20200217_Illumina_1":{
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"Nucleotide GTR":0.0001321702730418466,
"original name":"epi_isl_416623_unknown_20200217_Illumina_1"
},
"epi_isl_416674_USA_20200311_Illumina_2":{
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"Nucleotide GTR":0.0001321640679695789,
"original name":"epi_isl_416674_USA_20200311_Illumina_2"
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"epi_isl_416675_USA_20200311_Illumina_1":{
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"Nucleotide GTR":0.0002658041904122336,
"original name":"epi_isl_416675_USA_20200311_Illumina_1"
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"epi_isl_416676_USA_20200311_Illumina_1":{
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"Nucleotide GTR":0.0001321875962503517,
"original name":"epi_isl_416676_USA_20200311_Illumina_1"
},
"epi_isl_416677_Washington_20200312_Illumina_1":{
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"Nucleotide GTR":0,
"original name":"epi_isl_416677_Washington_20200312_Illumina_1"
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"epi_isl_416684_Washington_20200314_Illumina_1":{
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"Nucleotide GTR":0,
"original name":"epi_isl_416684_Washington_20200314_Illumina_1"
},
"epi_isl_416689_Washington_20200314_Illumina_1":{
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"Nucleotide GTR":0.0001321698613492602,
"original name":"epi_isl_416689_Washington_20200314_Illumina_1"
},
"epi_isl_416692_Washington_20200314_Illumina_1":{
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"Nucleotide GTR":0.0001321698738065058,
"original name":"epi_isl_416692_Washington_20200314_Illumina_1"
},
"epi_isl_416695_Washington_20200313_Illumina_1":{
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"Nucleotide GTR":0.0001321698738328856,
"original name":"epi_isl_416695_Washington_20200313_Illumina_1"
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"epi_isl_416700_Washington_20200313_Illumina_1":{
"Global MG94xREV":0.0005267146815172169,
"Nucleotide GTR":0.0005288605904193373,
"original name":"epi_isl_416700_Washington_20200313_Illumina_1"
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"epi_isl_416706_Washington_20200313_Illumina_1":{
"Global MG94xREV":0.0001316422686165173,
"Nucleotide GTR":0.0001321698736724715,
"original name":"epi_isl_416706_Washington_20200313_Illumina_1"
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"epi_isl_416709_Washington_20200313_Illumina_1":{
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"Nucleotide GTR":0.0001324807350823091,
"original name":"epi_isl_416709_Washington_20200313_Illumina_1"
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"epi_isl_416716_Washington_20200313_Illumina_1":{
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"Nucleotide GTR":0.0001321731808715047,
"original name":"epi_isl_416716_Washington_20200313_Illumina_1"
},
"epi_isl_416720_Washington_20200313_Illumina_1":{
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"Nucleotide GTR":0.0001321858661835397,
"original name":"epi_isl_416720_Washington_20200313_Illumina_1"
},
"epi_isl_416728_Washington_20200313_Illumina_1":{
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"Nucleotide GTR":0.0001321612945214054,
"original name":"epi_isl_416728_Washington_20200313_Illumina_1"
},
"epi_isl_416739_South_Yorkshire_20200309_Nanopore_1":{
"Global MG94xREV":0,
"Nucleotide GTR":0,
"original name":"epi_isl_416739_South_Yorkshire_20200309_Nanopore_1"
},
"epi_isl_416750_ARA_20200306_Illumina_1":{
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"original name":"epi_isl_416750_ARA_20200306_Illumina_1"
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"original name":"epi_isl_416751_ARA_20200305_Illumina_2"
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"epi_isl_416752_ARA_20200304_Illumina_1":{
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"epi_isl_416756_ARA_20200306_Illumina_1":{
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"epi_isl_416831_New_York_City_20200316_Targeted_1":{
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"original name":"epi_isl_416831_New_York_City_20200316_Targeted_1"
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"epi_isl_417008_Li_ge_20200307_Nanopore_1":{
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"original name":"epi_isl_417008_Li_ge_20200307_Nanopore_1"
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"epi_isl_417017_Li_ge_20200314_Nanopore_2":{
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"original name":"epi_isl_417017_Li_ge_20200314_Nanopore_2"
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"epi_isl_417018_Li_ge_20200314_Nanopore_1":{
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"epi_isl_417019_Li_ge_20200314_Nanopore_1":{
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"original name":"epi_isl_417019_Li_ge_20200314_Nanopore_1"
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"epi_isl_417020_Li_ge_20200315_Nanopore_1":{
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"epi_isl_417024_Li_ge_20200315_Nanopore_1":{
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"epi_isl_417026_Utah_20200320_Illumina_1":{
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"original name":"epi_isl_417026_Utah_20200320_Illumina_1"
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"epi_isl_417030_New_South_Wales_20200124_Illumina_2":{
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"original name":"epi_isl_417030_New_South_Wales_20200124_Illumina_2"
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"epi_isl_417067_Washington_20200303_Illumina_1":{
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"original name":"epi_isl_417067_Washington_20200303_Illumina_1"
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"epi_isl_417070_Washington_20200303_Illumina_1":{
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"original name":"epi_isl_417070_Washington_20200303_Illumina_1"
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"epi_isl_417071_Washington_20200303_Illumina_1":{
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"original name":"epi_isl_417071_Washington_20200303_Illumina_1"
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"epi_isl_417081_Washington_20200302_Illumina_2":{
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"original name":"epi_isl_417081_Washington_20200302_Illumina_2"
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"epi_isl_417090_Washington_20200304_Illumina_1":{
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"Nucleotide GTR":0.0001357556455163889,
"original name":"epi_isl_417090_Washington_20200304_Illumina_1"
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"epi_isl_417094_Washington_20200228_Illumina_1":{
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"Nucleotide GTR":0.0006630324228843357,
"original name":"epi_isl_417094_Washington_20200228_Illumina_1"
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"epi_isl_417113_Washington_20200302_Illumina_1":{
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"original name":"epi_isl_417113_Washington_20200302_Illumina_1"
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"epi_isl_417130_Washington_20200305_Illumina_1":{
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"Nucleotide GTR":0.0001321699017766769,
"original name":"epi_isl_417130_Washington_20200305_Illumina_1"
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"epi_isl_417136_Washington_20200305_Illumina_1":{
"Global MG94xREV":0.0001316324490308621,
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"original name":"epi_isl_417136_Washington_20200305_Illumina_1"
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"epi_isl_417138_Washington_20200305_Illumina_1":{
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"Nucleotide GTR":0.000132160604225485,
"original name":"epi_isl_417138_Washington_20200305_Illumina_1"
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"epi_isl_417165_Washington_20200308_Illumina_1":{
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"Nucleotide GTR":0.0001321698736600138,
"original name":"epi_isl_417165_Washington_20200308_Illumina_1"
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"epi_isl_417166_Washington_20200229_Illumina_1":{
"Global MG94xREV":0.0001316494846528295,
"Nucleotide GTR":0.0001321698738281031,
"original name":"epi_isl_417166_Washington_20200229_Illumina_1"
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"epi_isl_417168_Washington_20200229_Illumina_2":{
"Global MG94xREV":0.0001316499599364116,
"Nucleotide GTR":0.0001321699974102717,
"original name":"epi_isl_417168_Washington_20200229_Illumina_2"
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"epi_isl_417174_Washington_20200301_Illumina_1":{
"Global MG94xREV":0.0001316484584456098,
"Nucleotide GTR":0.0001321698806637888,
"original name":"epi_isl_417174_Washington_20200301_Illumina_1"
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"EBF site 2000 (partition 1)":{
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"EBF site 2005 (partition 1)":{
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"EBF site 2011 (partition 1)":{
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"EBF site 2016 (partition 1)":{
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"EBF site 2017 (partition 1)":{
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"attribute type":"branch label",
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"EBF site 2019 (partition 1)":{
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"EBF site 2020 (partition 1)":{
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"EBF site 2296 (partition 1)":{
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"display order":2316
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"EBF site 2325 (partition 1)":{
"attribute type":"branch label",
"display order":2327
},
"EBF site 2328 (partition 1)":{
"attribute type":"branch label",
"display order":2330
},
"EBF site 2335 (partition 1)":{
"attribute type":"branch label",
"display order":2337
},
"EBF site 2347 (partition 1)":{
"attribute type":"branch label",
"display order":2349
},
"EBF site 237 (partition 1)":{
"attribute type":"branch label",
"display order":239
},
"EBF site 2370 (partition 1)":{
"attribute type":"branch label",
"display order":2372
},
"EBF site 2371 (partition 1)":{
"attribute type":"branch label",
"display order":2373
},
"EBF site 2378 (partition 1)":{
"attribute type":"branch label",
"display order":2380
},
"EBF site 2388 (partition 1)":{
"attribute type":"branch label",
"display order":2390
},
"EBF site 2404 (partition 1)":{
"attribute type":"branch label",
"display order":2406
},
"EBF site 2426 (partition 1)":{
"attribute type":"branch label",
"display order":2428
},
"EBF site 2429 (partition 1)":{
"attribute type":"branch label",
"display order":2431
},
"EBF site 2433 (partition 1)":{
"attribute type":"branch label",
"display order":2435
},
"EBF site 2439 (partition 1)":{
"attribute type":"branch label",
"display order":2441
},
"EBF site 2454 (partition 1)":{
"attribute type":"branch label",
"display order":2456
},
"EBF site 2457 (partition 1)":{
"attribute type":"branch label",
"display order":2459
},
"EBF site 2458 (partition 1)":{
"attribute type":"branch label",
"display order":2460
},
"EBF site 2465 (partition 1)":{
"attribute type":"branch label",
"display order":2467
},
"EBF site 2478 (partition 1)":{
"attribute type":"branch label",
"display order":2480
},
"EBF site 2515 (partition 1)":{
"attribute type":"branch label",
"display order":2517
},
"EBF site 2530 (partition 1)":{
"attribute type":"branch label",
"display order":2532
},
"EBF site 2534 (partition 1)":{
"attribute type":"branch label",
"display order":2536
},
"EBF site 2560 (partition 1)":{
"attribute type":"branch label",
"display order":2562
},
"EBF site 2562 (partition 1)":{
"attribute type":"branch label",
"display order":2564
},
"EBF site 2564 (partition 1)":{
"attribute type":"branch label",
"display order":2566
},
"EBF site 2582 (partition 1)":{
"attribute type":"branch label",
"display order":2584
},
"EBF site 2585 (partition 1)":{
"attribute type":"branch label",
"display order":2587
},
"EBF site 2600 (partition 1)":{
"attribute type":"branch label",
"display order":2602
},
"EBF site 2601 (partition 1)":{
"attribute type":"branch label",
"display order":2603
},
"EBF site 2608 (partition 1)":{
"attribute type":"branch label",
"display order":2610
},
"EBF site 2609 (partition 1)":{
"attribute type":"branch label",
"display order":2611
},
"EBF site 2611 (partition 1)":{
"attribute type":"branch label",
"display order":2613
},
"EBF site 2614 (partition 1)":{
"attribute type":"branch label",
"display order":2616
},
"EBF site 2621 (partition 1)":{
"attribute type":"branch label",
"display order":2623
},
"EBF site 2627 (partition 1)":{
"attribute type":"branch label",
"display order":2629
},
"EBF site 2629 (partition 1)":{
"attribute type":"branch label",
"display order":2631
},
"EBF site 2637 (partition 1)":{
"attribute type":"branch label",
"display order":2639
},
"EBF site 264 (partition 1)":{
"attribute type":"branch label",
"display order":266
},
"EBF site 2642 (partition 1)":{
"attribute type":"branch label",
"display order":2644
},
"EBF site 2661 (partition 1)":{
"attribute type":"branch label",
"display order":2663
},
"EBF site 2662 (partition 1)":{
"attribute type":"branch label",
"display order":2664
},
"EBF site 2663 (partition 1)":{
"attribute type":"branch label",
"display order":2665
},
"EBF site 2666 (partition 1)":{
"attribute type":"branch label",
"display order":2668
},
"EBF site 2678 (partition 1)":{
"attribute type":"branch label",
"display order":2680
},
"EBF site 2691 (partition 1)":{
"attribute type":"branch label",
"display order":2693
},
"EBF site 2698 (partition 1)":{
"attribute type":"branch label",
"display order":2700
},
"EBF site 2706 (partition 1)":{
"attribute type":"branch label",
"display order":2708
},
"EBF site 2712 (partition 1)":{
"attribute type":"branch label",
"display order":2714
},
"EBF site 314 (partition 1)":{
"attribute type":"branch label",
"display order":316
},
"EBF site 318 (partition 1)":{
"attribute type":"branch label",
"display order":320
},
"EBF site 35 (partition 1)":{
"attribute type":"branch label",
"display order":37
},
"EBF site 372 (partition 1)":{
"attribute type":"branch label",
"display order":374
},
"EBF site 373 (partition 1)":{
"attribute type":"branch label",
"display order":375
},
"EBF site 374 (partition 1)":{
"attribute type":"branch label",
"display order":376
},
"EBF site 379 (partition 1)":{
"attribute type":"branch label",
"display order":381
},
"EBF site 386 (partition 1)":{
"attribute type":"branch label",
"display order":388
},
"EBF site 395 (partition 1)":{
"attribute type":"branch label",
"display order":397
},
"EBF site 397 (partition 1)":{
"attribute type":"branch label",
"display order":399
},
"EBF site 403 (partition 1)":{
"attribute type":"branch label",
"display order":405
},
"EBF site 406 (partition 1)":{
"attribute type":"branch label",
"display order":408
},
"EBF site 419 (partition 1)":{
"attribute type":"branch label",
"display order":421
},
"EBF site 434 (partition 1)":{
"attribute type":"branch label",
"display order":436
},
"EBF site 446 (partition 1)":{
"attribute type":"branch label",
"display order":448
},
"EBF site 452 (partition 1)":{
"attribute type":"branch label",
"display order":454
},
"EBF site 474 (partition 1)":{
"attribute type":"branch label",
"display order":476
},
"EBF site 475 (partition 1)":{
"attribute type":"branch label",
"display order":477
},
"EBF site 476 (partition 1)":{
"attribute type":"branch label",
"display order":478
},
"EBF site 503 (partition 1)":{
"attribute type":"branch label",
"display order":505
},
"EBF site 511 (partition 1)":{
"attribute type":"branch label",
"display order":513
},
"EBF site 517 (partition 1)":{
"attribute type":"branch label",
"display order":519
},
"EBF site 538 (partition 1)":{
"attribute type":"branch label",
"display order":540
},
"EBF site 555 (partition 1)":{
"attribute type":"branch label",
"display order":557
},
"EBF site 582 (partition 1)":{
"attribute type":"branch label",
"display order":584
},
"EBF site 591 (partition 1)":{
"attribute type":"branch label",
"display order":593
},
"EBF site 618 (partition 1)":{
"attribute type":"branch label",
"display order":620
},
"EBF site 619 (partition 1)":{
"attribute type":"branch label",
"display order":621
},
"EBF site 647 (partition 1)":{
"attribute type":"branch label",
"display order":649
},
"EBF site 671 (partition 1)":{
"attribute type":"branch label",
"display order":673
},
"EBF site 689 (partition 1)":{
"attribute type":"branch label",
"display order":691
},
"EBF site 71 (partition 1)":{
"attribute type":"branch label",
"display order":73
},
"EBF site 710 (partition 1)":{
"attribute type":"branch label",
"display order":712
},
"EBF site 713 (partition 1)":{
"attribute type":"branch label",
"display order":715
},
"EBF site 723 (partition 1)":{
"attribute type":"branch label",
"display order":725
},
"EBF site 725 (partition 1)":{
"attribute type":"branch label",
"display order":727
},
"EBF site 73 (partition 1)":{
"attribute type":"branch label",
"display order":75
},
"EBF site 749 (partition 1)":{
"attribute type":"branch label",
"display order":751
},
"EBF site 75 (partition 1)":{
"attribute type":"branch label",
"display order":77
},
"EBF site 764 (partition 1)":{
"attribute type":"branch label",
"display order":766
},
"EBF site 774 (partition 1)":{
"attribute type":"branch label",
"display order":776
},
"EBF site 794 (partition 1)":{
"attribute type":"branch label",
"display order":796
},
"EBF site 795 (partition 1)":{
"attribute type":"branch label",
"display order":797
},
"EBF site 797 (partition 1)":{
"attribute type":"branch label",
"display order":799
},
"EBF site 798 (partition 1)":{
"attribute type":"branch label",
"display order":800
},
"EBF site 8 (partition 1)":{
"attribute type":"branch label",
"display order":10
},
"EBF site 813 (partition 1)":{
"attribute type":"branch label",
"display order":815
},
"EBF site 820 (partition 1)":{
"attribute type":"branch label",
"display order":822
},
"EBF site 824 (partition 1)":{
"attribute type":"branch label",
"display order":826
},
"EBF site 828 (partition 1)":{
"attribute type":"branch label",
"display order":830
},
"EBF site 861 (partition 1)":{
"attribute type":"branch label",
"display order":863
},
"EBF site 866 (partition 1)":{
"attribute type":"branch label",
"display order":868
},
"EBF site 869 (partition 1)":{
"attribute type":"branch label",
"display order":871
},
"EBF site 88 (partition 1)":{
"attribute type":"branch label",
"display order":90
},
"EBF site 896 (partition 1)":{
"attribute type":"branch label",
"display order":898
},
"EBF site 9 (partition 1)":{
"attribute type":"branch label",
"display order":11
},
"EBF site 907 (partition 1)":{
"attribute type":"branch label",
"display order":909
},
"EBF site 913 (partition 1)":{
"attribute type":"branch label",
"display order":915
},
"EBF site 925 (partition 1)":{
"attribute type":"branch label",
"display order":927
},
"EBF site 947 (partition 1)":{
"attribute type":"branch label",
"display order":949
},
"EBF site 971 (partition 1)":{
"attribute type":"branch label",
"display order":973
},
"EBF site 975 (partition 1)":{
"attribute type":"branch label",
"display order":977
},
"EBF site 984 (partition 1)":{
"attribute type":"branch label",
"display order":986
},
"EBF site 987 (partition 1)":{
"attribute type":"branch label",
"display order":989
},
"EBF site 996 (partition 1)":{
"attribute type":"branch label",
"display order":998
},
"Global MG94xREV":{
"attribute type":"branch length",
"display order":1
},
"Nucleotide GTR":{
"attribute type":"branch length",
"display order":0
},
"original name":{
"attribute type":"node label",
"display order":-1
}
}
},
"data partitions":{
"0":{
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],
"name":"meme.filter.default"
}
},
"fits":{
"Global MG94xREV":{
"AIC-c":30111.63884681873,
"Equilibrium frequencies": [
[0.0309923350084511],
[0.01672113681686377],
[0.03238864857317798],
[0.02405155352264719],
[0.01556923117454071],
[0.00839998807872613],
[0.01627067973191633],
[0.01208247770936984],
[0.01138596334761356],
[0.006143010872698924],
[0.01189894099403551],
[0.008836059199390829],
[0.04644430746312961],
[0.02505786089507972],
[0.04853678666798558],
[0.03604303278430428],
[0.02025645426575106],
[0.01092886170434742],
[0.02116907868907461],
[0.01571998992069864],
[0.01017598122742256],
[0.005490195375829921],
[0.01063444492879846],
[0.00789705445136896],
[0.007441815718614311],
[0.004015044970406576],
[0.007777095659001681],
[0.005775209548203528],
[0.03035579570802993],
[0.01637770800684507],
[0.03172343094118168],
[0.02355756818565424],
[0.01527665080511974],
[0.008242133680673114],
[0.01596491758905093],
[0.01185542116739308],
[0.007674339732478567],
[0.004140497468515232],
[0.008020095696521297],
[0.005955659448581538],
[0.005612335633760871],
[0.003027994888693783],
[0.005865191069567286],
[0.004355444365377804],
[0.02289319171357612],
[0.01235144724374639],
[0.02392461042148705],
[0.01776622592822242],
[0.01495856176034741],
[0.02151627923036751],
[0.01392807849347979],
[0.00751454532296412],
[0.01455558735738835],
[0.01080886371621285],
[0.005495476087551538],
[0.01064467360631249],
[0.007904650186156685],
[0.04154861294497167],
[0.0224165117411884],
[0.04342052391375898],
[0.03224373664537515]
],
"Log Likelihood":-14536.42695060383,
"Rate Distributions":{
"non-synonymous/synonymous rate ratio for *background*": [
[0.7442297332630722, 1]
],
"non-synonymous/synonymous rate ratio for *test*": [
[0.9427603077052731, 1]
]
},
"display order":1,
"estimated parameters":519
},
"Nucleotide GTR":{
"AIC-c":31023.66397968627,
"Equilibrium frequencies": [
[0.2966437550312712],
[0.1866070313426554],
[0.1939082128189708],
[0.3228410008071025]
],
"Log Likelihood":-15000.70522818792,
"Rate Distributions":{
"Substitution rate from nucleotide A to nucleotide C":0.4587891463431998,
"Substitution rate from nucleotide A to nucleotide G":1,
"Substitution rate from nucleotide A to nucleotide T":0.4177145785603005,
"Substitution rate from nucleotide C to nucleotide G":0.5735415310566225,
"Substitution rate from nucleotide C to nucleotide T":1.770796247360479,
"Substitution rate from nucleotide G to nucleotide T":0.8186256790814425
},
"display order":0,
"estimated parameters":511
}
},
"input":{
"file name":"/Users/sergei/Dropbox/COVID-19/data/fasta/20200324/sequences.ORF1b.compressed.fas",
"number of sequences":253,
"number of sites":2720,
"partition count":1,
"trees":{
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